5 Most Insane Lab Created Hybrids & Animals – Top5s
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5 Most Insane Lab Created Hybrids & Animals

22 Jul 2018

Laboratories are the hub of life changing medicines and treatments, from cancer research to brain research… But not everything that takes place in the lab has a happy ending, something I have always had a strong thought about, is that their are things going on in secret labs that are so shocking and unheard of they could never be made public…

Just think about it, do you think for one minute, if an animal was somehow cloned, or a monstrous hybrid humanoid was created we would ever hear about… I personally think we are kept in the dark about such things…

But from two headed dogs, to human pigs, here are five most insane lab created hybrids, experiments and even success stories that we do know of…

5Monkey Head Transplant by Robert J. White

Robert Joseph White was a controversial America Neurosurgeon who performed over 10,000 surgical procedures and wrote numerous papers on neurosurgery, healthcare and medical ethics.

However, he is best known for performing head transplants on live monkeys, and in 1970 after many years of research and preparatory testing on Rhesus Monkeys, he successfully transplanted one monkey head onto the body of another.

The crude surgery involved cutting the animal’s spine at the neck, to remove their heads and transplanting one of the heads onto the other’s body.

Remarkable the monkey with the transplanted head lived for nine days and because the cranial nerves were still intact and supported by the circulatory system of the new body the monkey could still hear, taste, smell, eat and follow objects with its eyes.

Ultimately the monkey died as the body rejected the transplanted head.

Despite this in the 1990s, White announced that he planned to perform the same operation on humans and practised on cadavers at a morgue. He hoped that he could do head transplant surgery on the physicist Stephen Hawking and the paralysed actor Christopher Reeve.

However, he was unable to perfect the technique to be viable to use on humans….White died on September 16th, 2010 at the age of 84, and to date scientists are no nearer performing head transplants than they were in 1970 when Whites monkey died…

4The Shanghai Second Medical University Created The First Stable Human Cross Rabbit Chimaeras

In 2003 Chinese scientists at the Shanghai Second Medical University successfully combined rabbit eggs with human cells. The embryos were the first human-animal chimeras to be successfully developed, and the embryos were allowed to evolve for several days in a laboratory dish before they were destroyed and their stem cells were harvested. The hybrid embryos contained human and animal DNA.

Although this is not a new technique as previously human cells and cows eggs had been fused together, this is the only time the procedure has been successful, and scientists are hopeful that this would lead to a new and unlimited source of embryonic stem cells for research and, eventually, for medical use.

However, the ethics of such a procedure were brought into question, and some theorized about what monster would be created if the embryos were transferred to a womb to develop…

3Two Headed Dog

In 1937  young scientist 21-year-old Vladimir Demikhov designed the first ever cardiac assist machine, a pump mechanism that was able to take over a hearts cardiac function for a full five and a half hours. This was a  groundbreaking invention.

But, Demikhov’s research took a different direction when in 1946 he completed a heart transplant on a dog. Remarkably the dog survived for five months, and he continued performing transplants on dogs and successfully transplanted a lung and a cardiovascular bypass, and he soon became highly respected in the medical community. With some crediting him with having the most significant early impact on the study of heart and lung transplants than any other person in history.

Yet, despite this pioneering research that probably paved the way for the human heart and lung transplants we see today.  Demikhov is better remembered for his bizarre creation of living breathing two-headed dogs.

One day after completing a heart transplant procedure on a dog, Demikhov decided to carry out another experiment using the dog’s head, he wanted to see if he could keep just the head of the animal alive. He removed the head and pumped it with oxygen-rich blood and other nutrients, in order to feed the brain. Astonishingly the experiment was somewhat successful.

Buoyed by this success Demikhov took things a step further and by the mid-1950’s he had developed a technique where he transplanted a dogs head onto another dog’s body, the transplanted second head of the dog was able to see, eat and drink and the dog it was transplanted onto also remained alert and stable.

Many of the two-headed dogs lived for many months even though the burden and cardiovascular demands of the second head were hard for the original dog to maintain; meaning it could barely lift its own head off the floor, as the second head fed off its resources.

When the Soviet Ministry of Health reviewed Demikhov’s barbaric experiments, they declared his work was unethical, and he was instructed to stop his research.

Demikhov was addicted though, and despite warnings continued with his cruel experiments, eventually, the potentially brilliant scientist was ostracized by the medical community and labelled the “mad scientist.”

Demikhov died at the age of 82 in 1998, he was penniless, forgotten and living in poverty…

2Karl August Weinhold’s Experiments

In 1817 a Notorious Prussian Physician called Karl August Weinhold carried out a series of macabre experiments on Kittens to prove that he could bring animals back from the dead…… If you are an animal lover as am I, then you may find some of this disturbing.

In previous experiments, Weinhold had discovered what he called “bimetallic electricity” where he could generate an electrical charge by placing certain metals in contact with one another that he believed were capable of stimulating nerves and muscles in dead animals and ultimately humans.

Weinhold’s first experiment was on a three-week-old kitten. He chopped it’s head off, and the animal died immediately, he then applied his electrical charge to the dead creature’s muscles, and they automatically responded. Thrilled by the response he then cut out the headless kittens spinal cord and filled it with an amalgam of silver and zinc which he claimed created bimetallic electricity that restarted the kitten’s heart, and it stood up momentarily before dying for the second time.

Weinhold was excited by the response and acquired another kitten, and this time he removed its brain and filled the cavity with the same metallic liquid. He claimed that the electrically charged cat raised it’s head and opened its eyes and tried to crawl and jump before becoming exhausted and collapsing. Weinhold maintained the poor kitten was alive for at least 20 mins and he became convinced this was proof he could bring dead animals back to life and conducted several more experiments and poor defenceless creatures.

Unsurprisingly no one has ever successfully replicated Weinhold bizarre experiments, and let’s hope they never will…

1Human Cross Pig

In early 2017 scientists revealed they had created a human/pig hybrid…. but it’s probably not how you think….

Human stem cells were injected into early stage pig embryos and then transplanted into surrogate pigs, the embryos were then allowed to progress in the surrogate pig’s womb until they were around 28 days old….which is equal to the first trimester of a normal pig pregnancy.

The embryos were then extracted from the pig. Tests on the removed embryos showed that although they were predominantly pig, they did have around 10,000 human cells and this opened up the possibility of being able to grow human organs inside of animals for use in human transplants to generate human hearts, livers and kidneys.

However, it is thought that functional and transplantable tissue or organs created this way is a long way off, and the ethical concerns are hampering the progress and the chances of an intelligent hybrid creature with a humanised brain accidentally being released into the wild is not impossible although highly unlikely due to the restrictions in place…

To watch the Top5s video version of this article check out this link https://www.youtube.com/watch?v=qowNy8QwN2c

 

 

 

 









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